Wolfgang Sippl: search on Z-Library

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1

Compounds from African Medicinal Plants with Activities Against Selected Parasitic Diseases: Schistosomiasis, Trypanosomiasis and Leishmaniasis

Simoben, Conrad V., Ntie-Kang, Fidele, Akone, Sergi H., Sippl, Wolfgang

Journal:

Natural Products and Bioprospecting

Year:

2018

Language:

english

File:

PDF, 1.31 MB

english, 2018

2

Bioactive natural products derived from the Central African flora against neglected tropical diseases and HIV

Zofou, Denis, Ntie-Kang, Fidele, Sippl, Wolfgang, Efange, Simon M. N.

Journal:

Natural Product Reports

Year:

2013

Language:

english

File:

PDF, 2.47 MB

english, 2013

3

[Methods and Principles in Medicinal Chemistry] Epigenetic Targets in Drug Discovery Volume 42 || Histone Modification Analysis Using Mass Spectrometry

Sippl, Wolfgang, Jung, Manfred

Year:

2009

Language:

english

File:

PDF, 245 KB

english, 2009

4

Epigenetic drug discovery special issue

Wolfgang Sippl, Manfred Jung

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 118 KB

english, 2011

5

The Chemistry and Biological Activities of Natural Products from Northern African Plant Families: From Taccaceae to Zygophyllaceae

Ntie-Kang, Fidele, Njume, Leonel E., Malange, Yvette I., Günther, Stefan, Sippl, Wolfgang, Yong, Joseph N.

Journal:

Natural Products and Bioprospecting

Year:

2016

Language:

english

File:

PDF, 1.54 MB

english, 2016

6

The potential of anti-malarial compounds derived from African medicinal plants: a review of pharmacological evaluations from 2013 to 2019

Bekono, Boris D., Ntie-Kang, Fidele, OnguÃ©nÃ©, Pascal Amoa, Lifongo, Lydia L., Sippl, Wolfgang, Fester, Karin, Owono, Luc C. O.

Journal:

Malaria Journal

Year:

2020

File:

PDF, 3.00 MB

2020

7

Histone deacetylase inhibitors that target tubulin

Jörg Schemies, Wolfgang Sippl, Manfred Jung

Journal:

Year:

2009

Language:

english

File:

PDF, 518 KB

english, 2009

8

Assessing the pharmacokinetic profile of the CamMedNP natural products database: anin silicoapproach

Ntie-Kang, Fidele, Mbah, James A, Lifongo, Lydia L, Owono Owono, Luc C, Megnassan, Eugene, Meva'a Mbaze, Luc, Judson, Philip N, Sippl, Wolfgang, Efange, Simon MN

Journal:

Organic and Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 461 KB

english, 2013

9

Neues zum alten Histamin I. Ein weiteres Mitglied in der Rezeptorfamilie

Holger Stark, Birgit Schlegel, Wolfgang Sippl

Journal:

Pharmazie in unserer Zeit

Year:

2003

Language:

german

File:

PDF, 115 KB

german, 2003

10

ChemInform Abstract: The Uniqueness and Therapeutic Value of Natural Products from West African Medicinal Plants. Part 2. Terpenoids, Geographical Distribution and Drug Discovery

Ntie-Kang, Fidele, Lifongo, Lydia L., Simoben, Conrad V., Babiaka, Smith B., Sippl, Wolfgang, Mbaze, Luc Meva'a

Journal:

Year:

2014

File:

PDF, 12 KB

2014

11

Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II

Platzer, Charlott, Najjar, Abdulkarim, Rohe, Alexander, Erdmann, Frank, Sippl, Wolfgang, Schmidt, Matthias

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.51 MB

english, 2018

12

ChemInform Abstract: The Uniqueness and Therapeutic Value of Natural Products from West African Medicinal Plants. Part 3. Least Abundant Compound Classes

Simoben, Conrad V., Ntie-Kang, Fidele, Lifongo, Lydia L., Babiaka, Smith B., Sippl, Wolfgang, Mbaze, Luc Meva'a

Journal:

Year:

2014

File:

PDF, 12 KB

2014

13

Pharmacophore modeling and in silico toxicity assessment of potential anticancer agents from African medicinal plants

Ntie-Kang, Fidele, Simoben, Conrad Veranso, Karaman, Berin, Ngwa, Valery Fuh, Judson, Philip Neville, Sippl, Wolfgang, Meva’a Mbaze, Luc

Journal:

Drug Design Development and Therapy

Year:

2016

Language:

english

File:

PDF, 3.82 MB

english, 2016

14

Combattre les maladies négligées en ciblant sélectivement leurs enzymes épigénétiques : le cas de la désacétylase 8 (HDAC8) de Schistosoma mansoni

Marek, Martin, Shaik, Tajith B., Jung, Manfred, Sippl, Wolfgang, Pierce, Raymond J., Romier, Christophe

Journal:

Biologie Aujourd hui

Year:

2016

Language:

english

File:

PDF, 1.51 MB

english, 2016

15

Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and PDGFR-β related to anticancer drug resistance

Fischer, Tim, Najjar, Karim, Totzke, Frank, Schächtele, Christoph, Sippl, Wolfgang, Ritter, Christoph, Hilgeroth, Andreas

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.23 MB

english, 2018

16

The uniqueness and therapeutic value of natural products from West African medicinal plants, part II: terpenoids, geographical distribution and drug discovery

Ntie-Kang, Fidele, Lifongo, Lydia L., Simoben, Conrad V., Babiaka, Smith B., Sippl, Wolfgang, Mbaze, Luc Meva'a

Journal:

Year:

2014

Language:

english

File:

PDF, 2.47 MB

english, 2014

17

The potential of anti-malarial compounds derived from African medicinal plants, part I: a pharmacological evaluation of alkaloids and terpenoids

Amoa Onguéné, Pascal, Ntie-Kang, Fidele, Lifongo, Lydia, Ndom, Jean, Sippl, Wolfgang, Mbaze, Luc

Journal:

Malaria Journal

Year:

2013

Language:

english

File:

PDF, 602 KB

english, 2013

18

Entwicklung von Histon-Desacetylaseinhibitoren. Potente Wirkstoffe vor allem bei Krebserkrankungen

Ralf Heinke, Wolfgang Sippl

Journal:

Pharmazie in unserer Zeit

Year:

2010

Language:

german

File:

PDF, 793 KB

german, 2010

19

Enantiomerically Pure 2-Methyltetrahydro-3-benzazepin-1-ols Selectively Blocking GluN2B Subunit Containing N -Methyl- d -aspartate Receptors

Tewes, Bastian, Frehland, Bastian, Schepmann, Dirk, Robaa, Dina, Uengwetwanit, Tanaporn, Gaube, Friedemann, Winckler, Thomas, Sippl, Wolfgang, Wünsch, Bernhard

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 4.43 MB

english, 2015

20

Skin Penetration and Metabolism of Topical Glucocorticoids in Reconstructed Epidermis and in Excised Human Skin

Anja Gysler, Burkhard Kleuser, Wolfgang Sippl, Katharina Lange, HansChristian Korting, Hans-Dieter Höltje, Monika Schäfer-Korting

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 2.17 MB

1999

21

The potential of anti-malarial compounds derived from African medicinal plants, part II: a pharmacological evaluation of non-alkaloids and non-terpenoids

Ntie-Kang, Fidele, Onguéné, Pascal, Lifongo, Lydia L, Ndom, Jean, Sippl, Wolfgang, Mbaze, Luc

Journal:

Malaria Journal

Year:

2014

Language:

english

File:

PDF, 362 KB

english, 2014

22

Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals)

Schiedel, Matthias, Herp, Daniel, Hammelmann, Sören, Swyter, Sören, Lehotzky, Attila, Robaa, Dina, Oláh, Judit, Ovádi, Judit, Sippl, Wolfgang, Jung, Manfred

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.05 MB

english, 2017

23

ChemInform Abstract: Design, Synthesis, and Structure—Activity Relationships of a Series of 3-[2-(1-Benzylpiperidin-4-yl)ethylamino]pyridazine Derivatives as Acetylcholinesterase Inhibitors.

Jean-Marie Contreras, Isabelle Parrot, Wolfgang Sippl, Yveline M. Rival, Camille G. Wermuth

Journal:

Year:

2001

File:

PDF, 28 KB

2001

24

Novel aspects in structure–activity relationships of profiled 1-aza-9-oxafluorenes as inhibitors of Alzheimer's disease-relevant kinases cdk1, cdk5 and gsk3β

Tell, Volkmar, Mahmoud, Kazem Ahmed, Wichapong, Kanin, Schächtele, Christoph, Totzke, Frank, Sippl, Wolfgang, Hilgeroth, Andreas

Journal:

Year:

2012

Language:

english

File:

PDF, 2.30 MB

english, 2012

25

Inhibitors to understand molecular mechanisms of NAD+-dependent deacetylases (sirtuins)

Michael Lawson, Urszula Uciechowska, Jörg Schemies, Tobias Rumpf, Manfred Jung, Wolfgang Sippl

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Year:

2010

Language:

english

File:

PDF, 1.48 MB

english, 2010

26

Target-Based Approach to Inhibitors of Histone Arginine Methyltransferases

Spannhoff, Astrid, Heinke, Ralf, Bauer, Ingo, Trojer, Patrick, Metzger, Eric, Gust, Ronald, Schüle, Roland, Brosch, Gerald, Sippl, Wolfgang, Jung, Manfred

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 337 KB

english, 2007

27

Homology Modeling of Parasite Histone Deacetylases to Guide the Structure-Based Design of Selective Inhibitors

Melesina, Jelena, Robaa, Dina, Pierce, Raymond J., Romier, Christophe, Sippl, Wolfgang

Journal:

Journal of Molecular Graphics and Modelling

Year:

2015

Language:

english

File:

PDF, 2.24 MB

english, 2015

28

Substituted 2-(2-aminopyrimidin-4-yl)pyridine-4-carboxylates as potent inhibitors of JumonjiC domain-containing histone demethylases

Roatsch, Martin, Robaa, Dina, Pippel, Martin, Nettleship, Joanne E, Reddivari, Yamini, Bird, Louise E, Hoffmann, Inga, Franz, Henriette, Owens, Raymond J, Schüle, Roland, Flaig, Ralf, Sippl, Wolfgang,

Journal:

Future Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.31 MB

english, 2016

29

Strukturbasierte Entwicklung einer Affinitätssonde für Sirtuin 2

Schiedel, Matthias, Rumpf, Tobias, Karaman, Berin, Lehotzky, Attila, Gerhardt, Stefan, Ovádi, Judit, Sippl, Wolfgang, Einsle, Oliver, Jung, Manfred

Journal:

Angewandte Chemie

Year:

2016

Language:

german

File:

PDF, 1.64 MB

german, 2016

30

How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A InhibitionâThe Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine

Wurzlbauer, Anne, RÃ¼ben, Katharina, GÃ¼rdal, Ece, Chaikuad, Apirat, Knapp, Stefan, Sippl, Wolfgang, Becker, Walter, Bracher, Franz

Journal:

Year:

2020

File:

PDF, 4.82 MB

2020

31

Homology modeling and molecular dynamics simulations of Dengue virus NS2B/NS3 protease: insight into molecular interaction

Kanin Wichapong, Somsak Pianwanit, Wolfgang Sippl, Sirirat Kokpol

Journal:

Journal of Molecular Recognition

Year:

2010

Language:

english

File:

PDF, 1.45 MB

english, 2010

32

ChemInform Abstract: The Chemistry and Bioactivity of Southern African Flora II: Flavonoids, Quinones and Minor Compound Classes

Babiaka, Smith B., Ntie-Kang, Fidele, Ndingkokhar, Bakoh, Mbah, James A., Sippl, Wolfgang, Yong, Joseph N.

Journal:

Year:

2015

File:

PDF, 12 KB

2015

33

Identification and Structure-Activity Relationship Studies of Small-Molecule Inhibitors of the Methyllysine Reader Protein Spindlin1

Robaa, Dina, Wagner, Tobias, Luise, Chiara, Carlino, Luca, McMillan, Joel, Flaig, Ralf, Schüle, Roland, Jung, Manfred, Sippl, Wolfgang

Journal:

Year:

2016

Language:

english

File:

PDF, 1.47 MB

english, 2016

34

Carbamates as Potential Prodrugs and a New Warhead for HDAC Inhibition

King, Kristina, Hauser, Alexander-Thomas, Melesina, Jelena, Sippl, Wolfgang, Jung, Manfred

Journal:

Year:

2018

Language:

english

File:

PDF, 2.82 MB

english, 2018

35

Synthesis and biological evaluation of triazolyl-substituted benzyloxyacetohydroxamic acids as LpxC inhibitors

Hoff, Katharina, Mielniczuk, Sebastian, Agoglitta, Oriana, Iorio, Maria Teresa, Caldara, Manlio, BÃ¼lbÃ¼l, Emre F., Melesina, Jelena, Sippl, Wolfgang, Holl, Ralph

Journal:

Bioorganic & Medicinal Chemistry

Year:

2020

File:

PDF, 2.15 MB

2020

36

Discovery of 4-Benzylamino-Substituted α-Carbolines as a Novel Class of Receptor Tyrosine Kinase Inhibitors

Dr. Martin Krug, Dr. Kanin Wichapong, German Erlenkamp, Prof. Dr. Wolfgang Sippl, Dr. Christoph Schächtele, Dr. Frank Totzke, Priv.-Doz. Dr. Andreas Hilgeroth

Journal:

Year:

2011

Language:

english

File:

PDF, 413 KB

english, 2011

37

Editorial: Pharmazie in unserer Zeit 3/2010

Theo Dingermann, Manfred Jung, Wolfgang Sippl

Journal:

Pharmazie in unserer Zeit

Year:

2010

Language:

german

File:

PDF, 132 KB

german, 2010

38

Discovery of substituted sulfonamides and thiazolidin-4-one derivatives as agonists of human constitutive androstane receptor

Jenni Küblbeck, Johanna Jyrkkärinne, Antti Poso, Miia Turpeinen, Wolfgang Sippl, Paavo Honkakoski, Björn Windshügel

Journal:

Biochemical Pharmacology

Year:

2008

Language:

english

File:

PDF, 742 KB

english, 2008

39

The chemistry and bioactivity of Southern African flora II: flavonoids, quinones and minor compound classes

Babiaka, Smith B., Ntie-Kang, Fidele, Ndingkokhar, Bakoh, Mbah, James A., Sippl, Wolfgang, Yong, Joseph N.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.65 MB

english, 2015

40

Stabilization of the thermolabile variant S113L of carnitine palmitoyltransferase II

Motlagh, Leila, Golbik, Ralph, Sippl, Wolfgang, Zierz, Stephan

Journal:

Neurology: Genetics

Year:

2016

Language:

english

File:

PDF, 790 KB

english, 2016

41

Elastin is heterogeneously cross-linked

Schräder, Christoph U., Heinz, Andrea, Majovsky, Petra, Karaman, Berin, Brinckmann, Jürgen, Sippl, Wolfgang, Schmelzer, Christian E. H.

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 1.70 MB

english, 2018

42

Different antagonist binding properties of human and rat histamine H3 receptors

Holger Stark, Wolfgang Sippl, Xavier Ligneau, Jean-Michel Arrang, C.Robin Ganellin, Jean-Charles Schwartz, Walter Schunack

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 720 KB

english, 2001

43

Postprocessing of molecular docking poses using binding free energy calculations

Kanin Wichapong, Wolfgang Sippl

Journal:

Journal of Cheminformatics

Year:

2012

Language:

english

File:

PDF, 72 KB

english, 2012

44

The role of histone demethylases in cancer therapy

Hoffmann, Inga, Roatsch, Martin, Schmitt, Martin L., Carlino, Luca, Pippel, Martin, Sippl, Wolfgang, Jung, Manfred

Journal:

Molecular Oncology

Year:

2012

Language:

english

File:

PDF, 1.57 MB

english, 2012

45

Malony-CoA inhibits the S113L variant of carnitine-palmitoyltransferase II

Motlagh, Leila, Golbik, Ralph, Sippl, Wolfgang, Zierz, Stephan

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2016

Language:

english

File:

PDF, 762 KB

english, 2016

46

Stereospecific capillary electrophoresis assays using pentapeptide substrates for the study of aspergillus nidulans methionine sulfoxide reductase a and mutant enzymes

Zhu, Qingfu, El-Mergawy, Rabab G., Zhou, Yuzhen, Chen, Chunyang, Heinemann, Stefan H., Schönherr, Roland, Robaa, Dina, Sippl, Wolfgang, Scriba, Gerhard K. E.

Journal:

ELECTROPHORESIS

Year:

2016

Language:

english

File:

PDF, 1011 KB

english, 2016

47

Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors

Rüben, Katharina, Wurzlbauer, Anne, Walte, Agnes, Sippl, Wolfgang, Bracher, Franz, Becker, Walter, Herault, Yann

Journal:

Year:

2015

Language:

english

File:

PDF, 3.94 MB

english, 2015

48

Design of selective histone deacetylase inhibitors: rethinking classical pharmacophore

Melesina, Jelena, Praetorius, Lucas, Simoben, Conrad V, Robaa, Dina, Sippl, Wolfgang

Journal:

Future Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 168 KB

english, 2018

49

[Methods and Principles in Medicinal Chemistry] Epigenetic Drug Discovery || Front Matter

Sippl, Wolfgang, Jung, Manfred

Year:

2019

Language:

english

File:

PDF, 115 KB

english, 2019

50

Ubiquitin-specific proteases as cancer drug targets

Sippl, Wolfgang, Collura, Vincent, Colland, Frédéric

Journal:

Future Oncology

Year:

2011

Language:

english

File:

PDF, 3.07 MB

english, 2011

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